Botulinum toxin (Botox, Xeomin) is a neurotoxin produced by the bacterium Clostridium A. Botulinum toxin can relax the muscles of the face and neck which cause wrinkles associated with facial expressions or facial pain. Botox can cause facial expression lines or wrinkles to be less noticeable or essentially disappear. Areas most frequently treated are a) glabellar area of frown lines (located between the eyes); b) crow’s feet (lateral areas of the eyes); c) forehead wrinkles; d) radial lip lines (smoker’s lines); and e) head and neck muscles. Botox is diluted into a very controlled solution and is nearly painless when injected into the muscles using a thin needle. Patients may feel a slight burning sensation while the solution is being injected. The procedure takes about 20-25 minutes, and the results can last up to three months. With repeated treatments, the results tend to last longer.